Pantoprazole inhibits the secretion of hydrochloric acid in the stomach by specific action on the proton pumps of the parietal cells. The inhibition is dose dependent and affects both basal and stimulated acid secretion. In most patients, freedom from symptoms is achieved in 2 weeks. As with other proton pump inhibitors and H2 receptor inhibitors, treatment with pantoprazole causes a reduced acidity in the stomach and thereby an increase in gastrin in proportion to the reduction in acidity. The increase in gastrin is reversible.
Panrazol 20mg, 40mg (PDF, 82KB)